Avian CD154 enhances humoral and cellular immune responses induced by an adenovirus vector-based vaccine in chickens.

@article{Ramos2011AvianCE,
  title={Avian CD154 enhances humoral and cellular immune responses induced by an adenovirus vector-based vaccine in chickens.},
  author={Oliberto S{\'a}nchez Ramos and Alain Gonz{\'a}lez Pose and Silvia G{\'o}mez-Puerta and Julia Noda Gomez and Armando Vega Redondo and Julio C{\'e}sar {\'A}guila Benites and Lester Su{\'a}rez Amar{\'a}n and Natalie C. Parra and Jorge R Toledo Alonso},
  journal={Comparative immunology, microbiology and infectious diseases},
  year={2011},
  volume={34 3},
  pages={259-65}
}
Recombinant adenoviral vectors have emerged as an attractive system for veterinary vaccines development. However, for poultry vaccination a very important criterion for an ideal vaccine is its low cost. The objective of this study was to test the ability of chicken CD154 to enhance the immunogenicity of an adenoviral vector-based vaccine against avian influenza virus in order to reduce the amount of antigen required to induce an effective immune response in avian. Chickens were vaccinated with… CONTINUE READING
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