Averting inflammation by targeting the cytokine environment

@article{Kopf2010AvertingIB,
  title={Averting inflammation by targeting the cytokine environment},
  author={Manfred Kopf and M F Bachmann and Benjamin J Marsland},
  journal={Nature Reviews Drug Discovery},
  year={2010},
  volume={9},
  pages={703-718}
}
Cytokines are key instigators and regulators of immune responses and therefore hold great potential as targets for new therapeutic strategies. However, the selection of which cytokines to target, and in particular the identification of which cytokines regulate the rate-limiting steps of disease pathways, is crucial to the success of such strategies. Moreover, balancing the need for ablating pathological inflammatory responses and simultaneously maintaining the ability to control infectious… CONTINUE READING

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