Aversive and non-aversive memory impairment in the mucopolysaccharidosis II mouse model

Abstract

Hunter syndrome (MPS II, OMIM 309900) is a lysosomal storage disorder due to deficient iduronate sulphatase activity. Patients present multiple cognitive alterations, and the aim of this work was to verify if MPS II mice also present some progressive cognitive alterations. For that, MPS II mice from 2 to 6 months of age were submitted to repeated open field… (More)
DOI: 10.1007/s11011-017-0110-5

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