Aversive and Appetitive Events Evoke the Release of Corticotropin-Releasing Hormone and Bombesin-Like Peptides at the Central Nucleus of the Amygdala

  title={Aversive and Appetitive Events Evoke the Release of Corticotropin-Releasing Hormone and Bombesin-Like Peptides at the Central Nucleus of the Amygdala},
  author={Zul Merali and Judy F. McIntosh and Pam Kent and David Michaud and Hymie Anisman},
  journal={The Journal of Neuroscience},
  pages={4758 - 4766}
There is wide agreement that corticotropin-releasing hormone (CRH) systems within the brain are activated by stressful stimuli. There is also mounting evidence for the role of bombesin (BN)-like peptides in the mediation of the stress response. To date, however, the extent to which other stimuli increase the activity of these peptidergic systems has received little attention. In the present investigation we validated and used in vivo microdialysis sampling followed by ex vivo radioimmunoassays… 

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  • E. PichM. Lorang F. Weiss
  • Biology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1995
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