Aversive Pavlovian Control of Instrumental Behavior in Humans

@article{Geurts2013AversivePC,
  title={Aversive Pavlovian Control of Instrumental Behavior in Humans},
  author={Dirk E. M. Geurts and Quentin J. M. Huys and Hanneke E. M. den Ouden and Roshan Cools},
  journal={Journal of Cognitive Neuroscience},
  year={2013},
  volume={25},
  pages={1428-1441}
}
Adaptive behavior involves interactions between systems regulating Pavlovian and instrumental control of actions. Here, we present the first investigation of the neural mechanisms underlying aversive Pavlovian–instrumental transfer using fMRI in humans. Recent evidence indicates that these Pavlovian influences on instrumental actions are action-specific: Instrumental approach is invigorated by appetitive Pavlovian cues but inhibited by aversive Pavlovian cues. Conversely, instrumental… 

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Serotonin and Aversive Pavlovian Control of Instrumental Behavior in Humans

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Data suggest that serotonin is selectively involved in Pavlovian inhibition due to aversive expectations and have implications for the understanding of the mechanisms underlying a range of affective, impulsive, and aggressive neuropsychiatric disorders.

Avoidance‐based human Pavlovian‐to‐instrumental transfer

TLDR
The results suggest that avoidance‐based PIT utilizes a similar neural mechanism to that seen with PIT in an appetitive context, which has implications for understanding mechanisms of drug‐seeking behavior during addiction and relapse.

Medial Amygdala Lesions Selectively Block Aversive Pavlovian–Instrumental Transfer in Rats

Pavlovian conditioned stimuli (CSs) play an important role in the reinforcement and motivation of instrumental active avoidance (AA). Conditioned threats can also invigorate ongoing AA responding

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