Aversive Learning in Adolescents: Modulation by Amygdala–Prefrontal and Amygdala–Hippocampal Connectivity and Neuroticism

@article{Tzschoppe2014AversiveLI,
  title={Aversive Learning in Adolescents: Modulation by Amygdala–Prefrontal and Amygdala–Hippocampal Connectivity and Neuroticism},
  author={Jelka Tzschoppe and Frauke Nees and Tobias Banaschewski and Gareth J. Barker and Christian B{\"u}chel and Patricia J. Conrod and Hugh Garavan and Andreas Heinz and Eva Loth and Karl Mann and Jean-Luc Martinot and Michael N. Smolka and J{\"u}rgen Gallinat and Aandreas Str{\"o}hle and Maren Struve and Marcella Rietschel and Gunter Schumann and Herta Flor},
  journal={Neuropsychopharmacology},
  year={2014},
  volume={39},
  pages={875-884}
}
Neuroticism involves a tendency for enhanced emotional and cognitive processing of negative affective stimuli and a propensity to worry and be anxious. It is known that this trait modulates fear learning and the activation of brain regions involved in it such as the amygdala, hippocampus, and prefrontal cortex and their connectivity. Thirty-nine (21 female) 14-year-old healthy adolescents participated in functional magnetic resonance imaging (fMRI) of aversive pavlovian differential delay… CONTINUE READING