Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people.

@article{White2011AverageDB,
  title={Average daily blood pressure, not office blood pressure, is associated with progression of cerebrovascular disease and cognitive decline in older people.},
  author={William B White and Leslie I Wolfson and Dorothy B. Wakefield and Charles B. Hall and Patrick Campbell and Nicola Moscufo and Julia Schmidt and Richard F. Kaplan and Godfrey Pearlson and Charles R. G. Guttmann},
  journal={Circulation},
  year={2011},
  volume={124 21},
  pages={2312-9}
}
BACKGROUND High blood pressure (BP) is a risk factor for cerebrovascular disease, including stroke. Little is known about the importance of BP on the progression of microvascular disease of the brain, which has been associated with functional decline in mobility and cognition in older people. METHODS AND RESULTS This was a prospective cohort of subjects 75 to 89 years of age to determine relations among vascular risk factors, white matter hyperintensity volume, and functional status. Ninety… CONTINUE READING
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