Corpus ID: 89215500

Avaliação do efeito das células-tronco mesenquimais na terapêutica da esquistossomose mansoni experimental

  title={Avaliaç{\~a}o do efeito das c{\'e}lulas-tronco mesenquimais na terap{\^e}utica da esquistossomose mansoni experimental},
  author={Vitor Hugo Sim{\~o}es Miranda},
Inflammation is a local defense mechanism, but, the lack of control of this reaction can cause severe tissue damage. Mesenchymal stem cells (MSCs) can differentiate into multiple cell types in vitro and in vivo, contributing, for example, for tissue repair. Furthermore, several studies have demonstrated that MSCs can interact with cells of the innate and adaptive immune system leading to a down-modulation of various effector functions, thus collaborating to reduce inflammation. However, the… Expand