Availability of low-threshold Ca2+ current in retinal ganglion cells.

@article{Lee2003AvailabilityOL,
  title={Availability of low-threshold Ca2+ current in retinal ganglion cells.},
  author={Sherwin Chan Kit Lee and Yuki Hayashida and Andrew T Ishida},
  journal={Journal of neurophysiology},
  year={2003},
  volume={90 6},
  pages={
          3888-901
        }
}
Spiking in central neurons depends on the availability of inward and outward currents activated by depolarization and on the activation and priming of currents by hyperpolarization. Of these processes, priming by hyperpolarization is the least described. In the case of T-type Ca2+ current availability, the interplay of hyperpolarization and depolarization has been studied most completely in expression systems, in part because of the difficulty of pharmacologically separating the Ca2+ currents… CONTINUE READING

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