Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster.

  title={Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster.},
  author={Mary Prout and Z Damania and Joyce Soong and Dianne K. Fristrom and James W. Fristrom},
  volume={146 1},
Integrins are evolutionarily conserved transmembrane alpha,beta heterodimeric receptors involved in cell-to-matrix and cell-to-cell adhesions. In Drosophila the position-specific (PS) integrins mediate the formation and maintenance of junctions between muscle and epidermis and between the two epidermal wing surfaces. Besides integrins, other proteins are implicated in integrin-dependent adhesion. In Drosophila, somatic clones of mutations in PS integrin genes disrupt adhesion between wing… CONTINUE READING
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