Autosomal dominant restless legs syndrome maps on chromosome 14q.

  title={Autosomal dominant restless legs syndrome maps on chromosome 14q.},
  author={Maria Teresa Bonati and Luigi Ferini-Strambi and Paolo Aridon and Alessandro Oldani and Marco Zucconi and Giorgio Casari},
  journal={Brain : a journal of neurology},
  volume={126 Pt 6},
Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible desire to move the extremities associated with paraesthesia/dysaesthesia. These symptoms occur predominantly at rest and worsen at night, resulting in nocturnal insomnia and chronic sleep deprivation. In this paper, we show significant evidence of linkage to a new locus for RLS on chromosome 14q13-21 region in a 30-member, three-generation Italian family affected by RLS and periodic leg movements in… 

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