Autosomal dominant polycystic kidney disease

@article{Torres2007AutosomalDP,
  title={Autosomal dominant polycystic kidney disease},
  author={Vicente E. Torres and Peter C. Harris and Yves Pirson},
  journal={The Lancet},
  year={2007},
  volume={369},
  pages={1287-1301}
}

Figures and Tables from this paper

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TLDR
A case of a young girl with Turner syndrome and associated short stature on growth hormone treatment who presented with cystic renal disease found to be autosomal dominant kidney disease is presented and it is proposed reevaluation of renal screening guidelines in this population due to the potential association of growth hormone and cyst proliferation.
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TLDR
The current role of surgical interventions such as cyst fenestration, partial hepatectomy, liver transplantation, and recent advances in current and medical therapies is reviewed.
Autosomal Dominant Polycystic Kidney Disease (ADPKD) Clinical Trials: A Critical Appraisal
TLDR
The natural course of ADPKD is often of progressive nature, eventually leading to ESRD in approximately 50 % of patients afflicted, and the cause of end-stage renal disease (ESRD) in 5–10 % of the prevalent patients on renal replacement therapy (RRT) worldwide.
Autosomal dominant polycystic kidney disease presenting with hepatic encephalopathy.
TLDR
Autosomal dominant polycystic kidney disease is the most frequent genetic cause of renal failure in adults and is slightly more severe in males than in females while symptoms generally increase with age.
The association between autosomal dominant polycystic kidney disease and cancer
TLDR
With detailed literature reviewing, it is believed that ADPKD patients have a higher risk of tumorigenesis and thus highly recommend being aware of tumorsigenesis during follow-up in patients with AD PKD.
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