Autosomal dominant branchio-oto-renal syndrome--localization of a disease gene to chromosome 8q by linkage in a Dutch family.

Abstract

Branchio-oto-renal syndrome (BOR) is an autosomal dominant disorder with variable clinical manifestations affecting branchial, renal and auditory development. Varying clinical expression of the disease between different families suggests that multiple loci may be involved. However, the possibility of genetic heterogeneity as the cause of clinical… (More)

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@article{Kumar1992AutosomalDB, title={Autosomal dominant branchio-oto-renal syndrome--localization of a disease gene to chromosome 8q by linkage in a Dutch family.}, author={S Kumar and William J. Kimberling and Judy B. Kenyon and Richard J. H. Smith and Henri A. M. Marres and Cor W R J Cremers}, journal={Human molecular genetics}, year={1992}, volume={1 7}, pages={491-5} }