Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats.

@article{Lewin2003AutoregulationIT,
  title={Autoregulation in the parathyroid glands by PTH/PTHrP receptor ligands in normal and uremic rats.},
  author={Ewa Lewin and Bartolom{\'e} Garfia and Yolanda Almad{\'e}n and Mariano Rodr{\'i}guez and Klaus Olgaard},
  journal={Kidney international},
  year={2003},
  volume={64 1},
  pages={63-70}
}
BACKGROUND The secretion of parathyroid hormone (PTH) from the parathyroid glands might be regulated by autocrine/paracrine factors. We have previously shown that N-terminal parathyroid hormone-related protein (PTHrP) enhanced the secretory PTH response to low calcium in vivo and in vitro in rat parathyroid glands. N-terminal PTHrP fragments are equipotent… CONTINUE READING