Autoregulation by glucose of hepatic glucose balance: permissive effect of insulin.

@article{Davidson1981AutoregulationBG,
  title={Autoregulation by glucose of hepatic glucose balance: permissive effect of insulin.},
  author={Michael B. Davidson},
  journal={Metabolism: clinical and experimental},
  year={1981},
  volume={30 3},
  pages={279-84}
}
To study the pathways involved and the effect of insulin on the autoregulation of hepatic glucose balance, isolated hepatocytes from normal, diabetic and treated diabetic rats were incubated with varying concentrations of glucose (100-400 mg/dl) with and without pyruvate (10 mM). New glucose production or utilization was calculated from the change in media… CONTINUE READING