Autoregulated induction of the acute-phase response transcription factor gene, agp/ebp.

@article{Chang1995AutoregulatedIO,
  title={Autoregulated induction of the acute-phase response transcription factor gene, agp/ebp.},
  author={C J Chang and B. J. Shen and Simon C. Lee},
  journal={DNA and cell biology},
  year={1995},
  volume={14 6},
  pages={529-37}
}
AGP/EBP (C/EBP beta) is a key transcription factor responsible for transcriptional induction of many acute-phase protein genes. To characterize the regulation of this gene, we have isolated the mouse genomic DNA and sequenced the 5'-regulatory region. Using nuclear extracts from lipopolysaccharide (LPS)-stimulated or unstimulated mouse liver, three protein factor-binding motifs, UF1(-376 to -352), UF2(-254 to -223), and UF3(-220 to -190), as well as two Sp1 motifs (-309 to -277, and -264 to… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…