Autoradiographic localization of relaxin binding sites in rat brain.

  title={Autoradiographic localization of relaxin binding sites in rat brain.},
  author={P L Osheroff and Heidi Phillips},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={88 15},
Relaxin is a member of the insulin family of polypeptide hormones and exerts its best understood actions in the mammalian reproductive system. Using a biologically active 32P-labeled human relaxin, we have previously shown by in vitro autoradiography specific relaxin binding sites in rat uterus, cervix, and brain tissues. Using the same approach, we describe here a detailed localization of human relaxin binding sites in the rat brain. Displaceable relaxin binding sites are distributed in… CONTINUE READING
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