Autoradiographic in vitro-examination of psoriatic skin before, during and after dithranol treatment

@article{Steigleder2004AutoradiographicIV,
  title={Autoradiographic in vitro-examination of psoriatic skin before, during and after dithranol treatment},
  author={G. Steigleder and H. Schumann and K. Lennartz},
  journal={Archiv f{\"u}r dermatologische Forschung},
  year={2004},
  volume={246},
  pages={231-235}
}
  • G. Steigleder, H. Schumann, K. Lennartz
  • Published 2004
  • Chemistry, Medicine
  • Archiv für dermatologische Forschung
  • SummaryAutoradiographic in vitro-examination of normal and of psoriatic skin, using the double labelling technique (1 µC thymidine-2-C14 and 10 µC thymidine-methyl-H3), revealed the usual increase of proliferative activity in psoriatic skin, approximately four times greater than normal. The cell cycle time was shortened. According to the data obtained by the double labelling technique a shortening of the DNA synthesis time was not found in vitro. Treatment with a dithranol-salicylic acid (10… CONTINUE READING
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