Autoradiographic evidence for hepatic lobular concentration gradient of bile acid derivative.

Abstract

Using an iodinated bile-acid analog with hepatic uptake and transport characteristics similar to conventional bile acids, the hepatic lobular gradient concept of Goresky was studied utilizing autoradiography. 125I-labeled cholylglycylhistamine (125I-CGH) was infused into the portal veins of male Sprague-Dawley rats and the livers were fixed for light… (More)

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Cite this paper

@article{Jones1980AutoradiographicEF, title={Autoradiographic evidence for hepatic lobular concentration gradient of bile acid derivative.}, author={Adrian Jones and Gary T. Hradek and R H Renston and K. Y. Wong and G. Karlaganis and Gustav Paumgartner}, journal={The American journal of physiology}, year={1980}, volume={238 3}, pages={G233-7} }