Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain : A. Mansour H. Khachaturian, M.E. Lewis, H. Akil and S.J. Watson, Neuroscience, 7 (1987) 2445–2464

@article{Mansour1987AutoradiographicDO,
  title={Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain : A. Mansour H. Khachaturian, M.E. Lewis, H. Akil and S.J. Watson, Neuroscience, 7 (1987) 2445–2464},
  author={Alfred Mansour and H Khachaturian and Michael E. Lewis and Huda Akil and Stanley J. Watson},
  journal={Pain},
  year={1987},
  volume={33}
}
While there is an abundance of pharmacological and biochemical evidence to suggest the existence of multiple opioid receptors, their precise localization within the brain is unclear. To help clarify this issue, the present study examined the distributions of the mu, delta, and kappa opioid receptor subtypes in the rat forebrain and midbrain using in vitro autoradiography. Mu and delta receptors were labeled with the selective ligands 3H-DAGO (Tyr- D-Ala-Gly-MePhe-Gly-ol), and 3H-DPDPE (D-Pen2… CONTINUE READING
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