Autopsy validation of 123I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB

@inproceedings{Thomas2017AutopsyVO,
  title={Autopsy validation of 123I-FP-CIT dopaminergic neuroimaging for the diagnosis of DLB},
  author={Alan J Thomas and Johannes Attems and Sean J. Colloby and John T. O'Brien and Ian G. McKeith and Rodney Walker and Lean Eng Lee and David Burn and Debra J. Lett and Zuzana Walker},
  booktitle={Neurology},
  year={2017}
}
OBJECTIVE To conduct a validation study of 123I-N-fluoropropyl-2b-carbomethoxy-3b-(4-iodophenyl) nortropane (123I-FP-CIT) SPECT dopaminergic imaging in the clinical diagnosis of dementia with Lewy bodies (DLB) with autopsy as the gold standard. METHODS Patients >60 years of age with dementia who had undergone 123I-FP-CIT imaging in research studies and who had donated their brain tissue to the Newcastle Brain Tissue Resource were included. All had structured clinical research assessments, and… CONTINUE READING

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