Autophosphorylation activation and inhibition by curcumin of the epidermal growth factor receptor reconstituted in liposomes.

Abstract

The epidermal growth factor receptor (EGFR) is a 170-kDa transmembrane protein with intrinsic protein kinase activity. It is involved in the regulation of essential cellular processes such as proliferation, differentiation, survival, and migration. An increase in EGFR activity has been correlated to malignant evolution of the cells. We have used… (More)
DOI: 10.1002/jmr.2194

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