Autophagy regulation and integration with cell signaling.

@article{HamacherBrady2012AutophagyRA,
  title={Autophagy regulation and integration with cell signaling.},
  author={Anne Hamacher-Brady},
  journal={Antioxidants & redox signaling},
  year={2012},
  volume={17 5},
  pages={756-65}
}
SIGNIFICANCE Study over the past decade has revealed the critical role of autophagy in homeostatic and stress cell signaling. Autophagy is an intracellular process whereby double-membrane structures termed autophagosomes deliver cellular components to lysosomes for their degradation. RECENT ADVANCES Targets of specific autophagy range from proteins to protein aggregates to organelles and intracellular pathogens. Accordingly, autophagy fulfills numerous physiological roles and its deregulation… CONTINUE READING
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