Autophagy paradox and ceramide.

  title={Autophagy paradox and ceramide.},
  author={Wenhui Jiang and Besim Ogretmen},
  journal={Biochimica et biophysica acta},
  volume={1841 5},
Sphingolipid molecules act as bioactive lipid messengers and exert their actions on the regulation of various cellular signaling pathways. Sphingolipids play essential roles in numerous cellular functions, including controlling cell inflammation, proliferation, death, migration, senescence, tumor metastasis and/or autophagy. Dysregulated sphingolipid metabolism has been also implicated in many human cancers. Macroautophagy (referred to here as autophagy) "self-eating" is characterized by… CONTINUE READING
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