Autophagy modulates dynamics of connexins at the plasma membrane in an ubiquitin- dependent manner


Different pathways contribute to the turnover of connexins, the main structural components of gap junctions (GJ). The cellular pool of connexins targeted to each pathway and the functional consequences of degradation through these degradative pathways remain unknown. In this work, we have focused on the contribution of macroautophagy to connexin degradation… (More)