Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2

@inproceedings{Zhang2015AutophagymediatedHR,
  title={Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extracellular signal-regulated kinases 1/2},
  author={Qiu-yu Zhang and Lin-Qing Wu and Tao Zhang and YAN-FEI HAN and Xu Lin},
  booktitle={Oncology reports},
  year={2015}
}
High mobility group box-B1 (HMGB1), an autophagy activator, is crucial in tumorigenesis. However, its extracellular role and signaling in gastric cancer remain unclear. Samples were collected from gastric cancer patients and healthy controls. Immunohistochemistry and immunocytochemistry were used to determine the localization of HMGB1 in gastric cancer… CONTINUE READING