Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs.

@article{Hashimoto2014AutophagyIN,
  title={Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs.},
  author={Daisuke Hashimoto and Merja Bl{\"a}uer and Masahiko Hirota and Niina H Ikonen and J. A. Sand and Johanna M. Laukkarinen},
  journal={European journal of cancer},
  year={2014},
  volume={50 7},
  pages={1382-90}
}
BACKGROUND AND AIM Autophagy is a regulated process of degradation and recycling of cellular constituents. The role of autophagy in pancreatic cancer is still not clear. Some studies indicate that in pancreatic cancer autophagy exerts cytoprotective effects, whereas others suggest that autophagy positively contributes to cell death by enhancing cytotoxicity of anticancer drugs. The aim of this study was to investigate the role of autophagy in pancreatic cancer, and to provide insights into new… CONTINUE READING
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