Autophagy induction enhances tetrandrine-induced apoptosis via the AMPK/mTOR pathway in human bladder cancer cells.

@article{Kou2017AutophagyIE,
  title={Autophagy induction enhances tetrandrine-induced apoptosis via the AMPK/mTOR pathway in human bladder cancer cells.},
  author={Bo Kou and Wei Liu and Xu Xu and Yang Yang and Qiuyue Yi and Fengwei Guo and Jianpeng Li and Jinsong Zhou and Qingshan Kou},
  journal={Oncology reports},
  year={2017},
  volume={38 5},
  pages={
          3137-3143
        }
}
Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the roots of Stephania tetrandra is a traditional Chinese medicine and exerts anticancer capacity in various types of cancers. Previous studies have shown that tetrandrine induces apoptosis in bladder cancer cells via activation of the caspase cascade. However, the underlying mechanism has not yet… CONTINUE READING