Autophagy in immunity and cell-autonomous defense against intracellular microbes.

@article{Deretic2011AutophagyII,
  title={Autophagy in immunity and cell-autonomous defense against intracellular microbes.},
  author={Vojo Deretic},
  journal={Immunological reviews},
  year={2011},
  volume={240 1},
  pages={92-104}
}
Autophagy was viewed until very recently primarily as a metabolic and intracellular biomass and organelle quality and quantity control pathway. It has now been recognized that autophagy represents a bona fide immunologic process with a wide array of roles in immunity. The immunologic functions of autophagy, as we understand them now, span both innate and adaptive immunity. They range from unique and sometimes highly specialized immunologic effectors and regulatory functions (referred to here as… CONTINUE READING
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