Autophagy in Retinal Ganglion Cells in a Rhesus Monkey Chronic Hypertensive Glaucoma Model

@article{Deng2013AutophagyIR,
  title={Autophagy in Retinal Ganglion Cells in a Rhesus Monkey Chronic Hypertensive Glaucoma Model},
  author={Shuifeng Deng and Mei Wang and Zhichao Yan and Zhen Tian and Hongrui Chen and Xuejiao Yang and Yehong Zhuo},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
  • Shuifeng Deng, Mei Wang, +4 authors Yehong Zhuo
  • Published 2013
  • Medicine, Biology
  • PLoS ONE
  • Primary open angle glaucoma (POAG) is a neurodegenerative disease characterized by physiological intraocular hypertension that causes damage to the retinal ganglion cells (RGCs). In the past, RGC damage in POAG was suggested to have been attributed to RGC apoptosis. However, in the present study, we applied a model closer to human POAG through the use of a chronic hypertensive glaucoma model in rhesus monkeys to investigate whether another mode of progressive cell death, autophagy, was… CONTINUE READING

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