Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis

@article{Barth2010AutophagyID,
  title={Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis},
  author={Julia M. I. Barth and J{\'a}nos Szabad and Ernst Hafen and Katrin K{\"o}hler},
  journal={Cell Death and Differentiation},
  year={2010},
  pages={-}
}
Autophagy, an evolutionarily conserved lysosome-mediated degradation, promotes cell survival under starvation and is controlled by insulin/target of rapamycin (TOR) signaling. In Drosophila, nutrient depletion induces autophagy in the fat body. Interestingly, nutrient availability and insulin/TOR signaling also influence the size and structure of Drosophila ovaries, however, the role of nutrient signaling and autophagy during this process remains to be elucidated. Here, we show that starvation… CONTINUE READING

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