Autophagy driven by a master regulator of hematopoiesis.

  title={Autophagy driven by a master regulator of hematopoiesis.},
  author={Y S Kang and Rajendran Sanalkumar and Henriette O'Geen and Amelia K Linnemann and Chan-Jung Chang and Eric E. Bouhassira and Peggy J. Farnham and S{\"u}nd{\"u}z Keles and Emery H. Bresnick},
  journal={Molecular and cellular biology},
  volume={32 1},
Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery functions in a multistep biochemical pathway. Though components of the autophagy machinery are broadly expressed, autophagy can occur in specialized cellular contexts, and mechanisms underlying cell-type-specific autophagy are poorly understood. We demonstrate that the master regulator of hematopoiesis, GATA-1, directly… CONTINUE READING
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