Autophagy contributes to ING4-induced glioma cell death.

  title={Autophagy contributes to ING4-induced glioma cell death.},
  author={Ai-hua Gong and Sisi Ye and Ermeng Xiong and Wenjie Guo and Yan Zhang and Wanxin Peng and Genbao Shao and Jie Jin and Zhijian Zhang and Jicheng Yang and Jing Gao},
  journal={Experimental cell research},
  volume={319 12},
Previous studies suggest that ING4, a novel member of ING (inhibitor of growth) family, can inhibit brain tumor growth. However, whether autophagy is involved in ING4-induced cell death still remains unknown. In this study, we found that in addition to apoptosis, autophagy also contributed to cell death induced by ING4. Autophagy levels were elevated… CONTINUE READING