Autophagy as an immune defense mechanism.

  title={Autophagy as an immune defense mechanism.},
  author={Vojo Deretic},
  journal={Current opinion in immunology},
  volume={18 4},
Autophagy is a homeostatic process whereby cytosol or intracellular organelles are sequestered by a double membrane structure termed autophagosome for subsequent delivery to lysosomes and degradation. Autophagy takes part in cell survival and death and has been implicated in development, aging, neurodegeneration and cancer. The newly discovered specialized role of autophagy in immune cells expands autophagic functions to defense against intracellular pathogens. Furthermore, autophagy is… CONTINUE READING
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