Autophagy and human disease.

  title={Autophagy and human disease.},
  author={Ju Huang and Daniel J Klionsky},
  journal={Cell cycle},
  volume={6 15},
As a conserved cellular degradative pathway in eukaryotes, autophagy relieves cells from various types of stress. There are different forms of autophagy, and the ongoing studies of the molecular mechanisms and cellular functions of these processes are unraveling their significant roles in human health. Currently, the best-studied of these pathways is macroautophagy, which is linked to a range of human disease. For example, as part of the host immune defense mechanism, macroautophagy is… CONTINUE READING
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