Autophagy and cellular immune responses.

  title={Autophagy and cellular immune responses.},
  author={Yuting Ma and Lorenzo Galluzzi and Laurence Zitvogel and Guido Kroemer},
  volume={39 2},
Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of various cytoplasmic structures, including damaged organelles and invading microorganisms. Autophagy not only represents an essential cell-intrinsic mechanism to protect against internal and external stress conditions but also shapes cellular immunity. Recent evidence indicates that autophagic responses in antigen-donor cells affect the release of several cytokines and "danger signals." Thus, especially when it… CONTINUE READING
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