Autophagy and ageing: implications for age-related neurodegenerative diseases.

@article{Carroll2013AutophagyAA,
  title={Autophagy and ageing: implications for age-related neurodegenerative diseases.},
  author={Bernadette Carroll and Graeme Hewitt and Viktor I. Korolchuk},
  journal={Essays in biochemistry},
  year={2013},
  volume={55},
  pages={
          119-31
        }
}
Autophagy is a process of lysosome-dependent intracellular degradation that participates in the liberation of resources including amino acids and energy to maintain homoeostasis. Autophagy is particularly important in stress conditions such as nutrient starvation and any perturbation in the ability of the cell to activate or regulate autophagy can lead to cellular dysfunction and disease. An area of intense research interest is the role and indeed the fate of autophagy during cellular and… Expand
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