Autophagy and Mammalian Viruses: Roles in Immune Response, Viral Replication, and Beyond.

@article{Paul2016AutophagyAM,
  title={Autophagy and Mammalian Viruses: Roles in Immune Response, Viral Replication, and Beyond.},
  author={P. Joses Paul and Christian M{\"u}nz},
  journal={Advances in virus research},
  year={2016},
  volume={95},
  pages={149-95}
}
Autophagy is an important cellular catabolic process conserved from yeast to man. Double-membrane vesicles deliver their cargo to the lysosome for degradation. Hence, autophagy is one of the key mechanisms mammalian cells deploy to rid themselves of intracellular pathogens including viruses. However, autophagy serves many more functions during viral infection. First, it regulates the immune response through selective degradation of immune components, thus preventing possibly harmful… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Similar Papers

Loading similar papers…