Autophagy and Immune-Related Diseases.

  title={Autophagy and Immune-Related Diseases.},
  author={Peng Tan and Youqiong Ye and Jingrong Mao and Lian He},
  journal={Advances in experimental medicine and biology},
  • P. Tan, Y. Ye, Lian He
  • Published 2019
  • Biology
  • Advances in experimental medicine and biology
Autophagy is an intracellular degradation and recycling machinery by which cellular materials are delivered to the lysosome for disposal. Beyond lysosomal degradation, autophagy genes play additional roles in secretion and membrane-trafficking pathways. Ranging from cell-intrinsic and cell-type-specific regulation of innate inflammatory signaling pathways to intercellular cross talk through secretion of soluble factors (e.g., shaping the MHC immunopeptidome for T cell response, etc.), autophagy… 
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