Autophagy-Inflammasome Interplay in Heart Failure: A Systematic Review on Basics, Pathways, and Therapeutic Perspectives.

@article{Chiu2017AutophagyInflammasomeII,
  title={Autophagy-Inflammasome Interplay in Heart Failure: A Systematic Review on Basics, Pathways, and Therapeutic Perspectives.},
  author={Bonnie Chiu and Eugeniu Jantuan and Fan Shen and Brian K Chiu and Consolato M Sergi},
  journal={Annals of clinical and laboratory science},
  year={2017},
  volume={47 3},
  pages={243-252}
}
Aging of the population contributes to the increasing prevalence of heart failure. Autophagy is an evolutionarily conserved process aiming to degrade both long-lived proteins and damaged or excessive cyto-organelles via the lysosomal-mediated pathway. Although autophagy is involved in the normal homeostasis of cardiovascular cells, upregulation of autophagy… CONTINUE READING