Autophagy: for better or for worse

  title={Autophagy: for better or for worse},
  author={Ellen Wirawan and Tom Vanden Berghe and Saskia Lippens and Patrizia Agostinis and Peter Vandenabeele},
  journal={Cell Research},
Autophagy is a lysosomal degradation pathway that degrades damaged or superfluous cell components into basic biomolecules, which are then recycled back into the cytosol. In this respect, autophagy drives a flow of biomolecules in a continuous degradation-regeneration cycle. Autophagy is generally considered a pro-survival mechanism protecting cells under stress or poor nutrient conditions. Current research clearly shows that autophagy fulfills numerous functions in vital biological processes… CONTINUE READING
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