Autophagy: dual roles in life and death?

  title={Autophagy: dual roles in life and death?},
  author={Eric H. Baehrecke},
  journal={Nature Reviews Molecular Cell Biology},
Autophagy is an evolutionarily conserved mechanism for the degradation of cellular components in the cytoplasm, and serves as a cell survival mechanism in starving cells. Recent studies indicate that autophagy also functions in cell death, but the precise role of this catabolic process in dying cells is not clear. Here I discuss the possible roles for autophagy in dying cells and how understanding the relationship between autophagy, cell survival and cell death is important for health and… CONTINUE READING
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