Autophagy: a regulated bulk degradation process inside cells.

  title={Autophagy: a regulated bulk degradation process inside cells.},
  author={Tamotsu Yoshimori},
  journal={Biochemical and biophysical research communications},
  volume={313 2},
Autophagy is a major intracellular degradation/recycling system ubiquitous in eukaryotic cells. It contributes to the turnover of cellular components by delivering portions of the cytoplasm and organelles to lysosomes, where they are digested. Autophagy is mediated by membrane trafficking of unique double-membrane structures, the so-called autophagosomes, which are formed transiently. Moreover, autophagy is dramatically induced under starvation conditions to maintain an amino acid pool so that… CONTINUE READING

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