Autophagic and apoptotic response to stress signals in mammalian cells.

  title={Autophagic and apoptotic response to stress signals in mammalian cells.},
  author={Elisabetta Ferraro and Francesco Cecconi},
  journal={Archives of biochemistry and biophysics},
  volume={462 2},
Autophagy is a highly conserved catabolic programme for degrading proteins and organelles. This process has been shown to act as a pro-survival or pro-death mechanism in different physiological and pathological conditions. Several stress stimuli can induce autophagy, such as nutrient deprivation or critical steps in development of lower and higher eukaryotes. Apoptosis is an orchestrated form of cell death in which cells are actively involved in their own demise. Again, stress is a positive… CONTINUE READING
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