Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis.

@article{Marshall2015AutophagicDO,
  title={Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis.},
  author={R. S. Marshall and F. Li and D. C. Gemperline and A. Book and R. Vierstra},
  journal={Molecular cell},
  year={2015},
  volume={58 6},
  pages={
          1053-66
        }
}
  • R. S. Marshall, F. Li, +2 authors R. Vierstra
  • Published 2015
  • Biology, Medicine
  • Molecular cell
  • Autophagic turnover of intracellular constituents is critical for cellular housekeeping, nutrient recycling, and various aspects of growth and development in eukaryotes. [...] Key Result Using Arabidopsis proteasomes tagged with GFP, we observed their deposition into vacuoles via a route requiring components of the autophagy machinery. This transport can be initiated separately by nitrogen starvation and chemical or genetic inhibition of the proteasome, implying distinct induction mechanisms.Expand Abstract
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    References

    SHOWING 1-10 OF 37 REFERENCES
    Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins
    • 200
    • Highly Influential
    A role for ubiquitin in selective autophagy.
    • 1,073
    Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates
    • 112
    • Highly Influential
    • PDF
    Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.
    • 637
    • Highly Influential
    The Defective Proteasome but Not Substrate Recognition Function Is Responsible for the Null Phenotypes of the Arabidopsis Proteasome Subunit RPN10[W][OA]
    • 42
    • Highly Influential
    • PDF
    Affinity Purification of the Arabidopsis 26 S Proteasome Reveals a Diverse Array of Plant Proteolytic Complexes*
    • 106
    • PDF
    Network organization of the human autophagy system
    • 1,254
    • PDF
    Dss1 Is a 26S Proteasome Ubiquitin Receptor
    • 67
    • PDF