Autonomic responses to cold face stimulation in sickle cell disease: a time-varying model analysis


Sickle cell disease (SCD) is characterized by sudden onset of painful vaso-occlusive crises (VOC), which occur on top of the underlying chronic blood disorder. The mechanisms that trigger VOC remain elusive, but recent work suggests that autonomic dysfunction may be an important predisposing factor. Heart-rate variability has been employed in previous… (More)
DOI: 10.14814/phy2.12463

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