Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with duration of disease.

@article{Cheng2013AutonomicRT,
  title={Autonomic response to a visceral stressor is dysregulated in irritable bowel syndrome and correlates with duration of disease.},
  author={Phillip M. Cheng and W. P. Shih and Melissa Alberto and Angela P. Presson and Arlene Licudine and Emeran A. Mayer and Bruce D. Naliboff and Lin Chang},
  journal={Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society},
  year={2013},
  volume={25 10},
  pages={e650-9}
}
BACKGROUND Previous studies reported altered autonomic nervous system (ANS) responses in irritable bowel syndrome (IBS) at baseline and to colonic balloon distension. This study examined heart rate variability (HRV) and plasma catecholamines as an index of ANS responsiveness in IBS during flexible sigmoidoscopy (FS) and explored associations of HRV with clinical measures. METHODS Rome III-positive IBS patients and healthy controls completed questionnaires measuring gastrointestinal and… CONTINUE READING

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