Autonomic control during acute hypoglycemia in type 1 diabetes mellitus

  title={Autonomic control during acute hypoglycemia in type 1 diabetes mellitus},
  author={Jacqueline K. Limberg and Kathryn E. Farni and Jennifer L. Taylor and Simmi Dube and Ananda Basu and Rita Basu and Erica A. Wehrwein and Michael J. Joyner},
  journal={Clinical Autonomic Research},
We hypothesized that adults with type 1 diabetes mellitus (T1DM) would exhibit impaired heart rate variability (HRV), QT interval, T-wave amplitude, and baroreflex sensitivity (BRS) when compared with healthy controls. In addition, we hypothesized that acute hypoglycemia would result in further adverse changes in measures of autonomic and cardiovascular function. A single 180-min hyperinsulinemic (2 mU/kg TBW/min), hypoglycemic (~3.3 umol/mL) clamp was completed in 10 healthy adults and 13… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 30 references

Similar Papers

Loading similar papers…