Autonomic cardiac regulation in obstructive sleep apnea syndrome: evidence from spontaneous baroreflex analysis during sleep.

@article{Parati1997AutonomicCR,
  title={Autonomic cardiac regulation in obstructive sleep apnea syndrome: evidence from spontaneous baroreflex analysis during sleep.},
  author={Gianfranco Parati and Marco di Rienzo and Maria R Bonsignore and Giuseppe Insalaco and Oreste Marrone and Paolo Castiglioni and Giovanni Bonsignore and Giuseppe Mancia},
  journal={Journal of hypertension},
  year={1997},
  volume={15 12 Pt 2},
  pages={1621-6}
}
OBJECTIVE To assess spontaneous baroreceptor-heart rate reflex sensitivity during sleep in patients with obstructive sleep apnea syndrome, a condition associated with increased cardiovascular morbidity and mortality and characterized by marked sympathetic activation, which is believed to originate from hypoxic chemoreceptor stimulation, although little is known of other possible mechanisms such as baroreflex impairment. DESIGN AND METHODS In 11 patients with severe obstructive sleep apnea… CONTINUE READING