Automatic generation of cellular reaction networks with Moleculizer 1.0

  title={Automatic generation of cellular reaction networks with Moleculizer 1.0},
  author={Larry Lok and Roger Brent},
  journal={Nature Biotechnology},
Accurate simulation of intracellular biochemical networks is essential to furthering our understanding of biological system behavior. The number of protein complexes and of chemical interactions among them has traditionally posed significant problems for simulation algorithms. Here we describe an approach to the exact stochastic simulation of biochemical networks that emphasizes the contribution of protein complexes to these systems. This simulation approach starts from a description of… CONTINUE READING
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